セキ　マサフミ   SEK Masafumi   関　雅文    所属   埼玉医科大学  医学部 国際医療センター　感染症科・感染制御科    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Clinical presentation of Legionella pneumonia: Evaluation of clinical scoring systems and therapeutic efficacy
掲載誌名	正式名：Journal of Infection and Chemotherapy ISSNコード：1341321X
出版社	Elsevier B.V.
巻・号・頁	23(11),727-732頁
著者・共著者	Naoyuki Miyashita,Futoshi Higa,Yosuke Aoki,Toshiaki Kikuchi,Masafumi Seki,Kazuhiro Tateda,Nobuko Maki,Kazuhiro Uchino,Kazuhiko Ogasawara,Hiroshi Kiyota,Akira Watanabe
発行年月	2017/11
概要	© 2017 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases To evaluate scoring systems to predict Legionella pneumonia and therapeutic efficacy against Legionella pneumonia, the Japanese Society of Chemotherapy Legionella committee has collected data on cases of Legionella pneumonia from throughout Japan. We analyzed 176 patients with Legionella pneumonia and compared them with 217 patients with Streptococcus pneumoniae pneumonia and 202 patients with Mycoplasma pneumoniae pneumonia. We evaluated four scoring systems, the Winthrop-University Hospital score, Community-Based Pneumonia Incidence Study Group score, and Japan Respiratory Society score, but they demonstrated limited sensitivity and specificity for predicting Legionella pneumonia. Using six clinical and laboratory parameters (high fever, high C-reactive protein, high lactate dehydrogenase, thrombocytopenia, hyponatremia, and unproductive cough) reported by Fiumefreddo and colleagues, only 6% had Legionnella pneumonia when less than 2 parameters were present. The efficacy rates of antibiotics at the time of termination were 94.6% for intravenous antibiotics, including ciprofloxacin and pa
DOI	10.1016/j.jiac.2017.09.001
PMID	28951197