セキ　マサフミ   SEK Masafumi   関　雅文    所属   埼玉医科大学  医学部 国際医療センター　感染症科・感染制御科    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Validation of a diagnostic score model for the prediction of Legionella pneumophila pneumonia
掲載誌名	正式名：Journal of Infection and Chemotherapy ISSNコード：1341321X
巻・号・頁	25(6),407-412頁
著者・共著者	Naoyuki Miyashita,Nobuyuki Horita,Futoshi Higa,Yosuke Aoki,Toshiaki Kikuchi,Masafumi Seki,Kazuhiro Tateda,Nobuko Maki,Kazuhiro Uchino,Kazuhiko Ogasawara,Hiroshi Kiyota,Akira Watanabe
発行年月	2019/06
概要	© 2019 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases Background: Community-acquired pneumonia (CAP) due to Legionella has a high mortality rate in patients who do not receive adequate antibiotic therapy. In a previous study, we developed a simple Legionella Score to distinguish patients with Legionella and non-Legionella pneumonia based on clinical information at diagnosis. In the present study, we validated this Legionella Score for the presumptive diagnosis of Legionella CAP. Methods: This validation cohort included 109 patients with Legionella CAP and 683 patients with non-Legionella CAP. The Legionella Score includes six parameters by assigning one point for each of the following items: being male, absence of cough, dyspnea, C-reactive protein (CRP) ≥ 18 mg/dL, lactate dehydrogenase (LDH) ≥ 260 U/L, and sodium<134 mmol/L. Results: When the Legionella CAP and non-Legionella CAP were compared by univariate analysis, most of the evaluated symptoms and laboratory test results differed substantially. The six parameters that were used for the Legionella Score also indicatedclear differences between the Legionella and non-Legionella CAP.
DOI	10.1016/j.jiac.2019.03.009
PMID	30935766