オバタ　ヒデアキ   OBATA Hideaki   小幡　英章    所属   埼玉医科大学  医学部 総合医療センター　麻酔科（麻酔科、産科麻酔科）    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Epidural block with mepivacaine before surgery reduces long-term post-thoracotomy pain
掲載誌名	正式名：CANADIAN JOURNAL OF ANAESTHESIA-JOURNAL CANADIEN D ANESTHESIE ISSNコード：0832610X
出版社	CANADIAN ANAESTHETISTS SOC INC
巻・号・頁	46(12),1127-1132頁
著者・共著者	H Obata,S Saito,N Fujita,Y Fuse,K Ishizaki,F Goto
発行年月	1999/12
概要	Purpose: To examine the effect of continuous epidural block initiated before thoracic surgery upon early and long-term postoperative pain.Methods: In a double-blind study, 70 patients scheduled for thoracic surgery under general anesthesia were assigned randomly to receive continuous epidural block with mepivacaine 1.5% initiated either 20 min before surgical incision (Pre group) or at completion of surgery (Post group). In both groups the initial dose was 4 mt, followed by a continuous infusion at 4 ml.hr(-1) until 72 hr after operation. Indomethacin suppositories, 50 mg, were administered on request as supplementary analgesics. Visual analogue scale at rest was assessed four hours after operation, and then every 24 hr after operation on postoperative days I through 7, and also days 14 and 30. At three and six months after operation, all patients were interviewed by telephone with respect to postoperative pain. The most severe pain was assessed using modified numerical rating scale.Results: By a visual analogue scale, postoperative pain was less in the Pre group than in the Post group at four hours, two and three days after operation (P< 0.05). By a numerical rating scale si
PMID	10608205