オバタ　ヒデアキ   OBATA Hideaki   小幡　英章    所属   埼玉医科大学  医学部 総合医療センター　麻酔科（麻酔科、産科麻酔科）    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	High predictive value of red cell volume measurement using carboxy haemoglobin in a rabbit model of haemorrhage
掲載誌名	正式名：BRITISH JOURNAL OF ANAESTHESIA ISSNコード：00070912
出版社	PROF SCI PUBL
巻・号・頁	81(6),940-944頁
著者・共著者	H Obata,F Goto,T Nara,F Kunimoto,N Oriuchi,E Mishiba,M Nemoto
発行年月	1998/12
概要	We have studied the accuracy of blood volume measurements using carbon monoxide (CO)labelled haemoglobin (COHb) injection and dilution (CO method) by comparing changes in red cell volume (RCV) measured using the CO method and Cr-51-labelled erythrocyte dilution (Cr-51 method) in a haemorrhage and infusion model in rabbits. RCV was measured repeatedly using the CO method at four different blood volumestages (stages I-IV). At stages I and IV, RCV was measured simultaneously using the Cr-51 method. In comparing the sum of the circulating RCV and extracted RCV (SUM RCV) using the CO method, the values were almost equal and there were no significant differences between the values at the four stages. In comparing circulating RCV measured using the CO method and the Cr-51 method, mean difference between the two methods was 0.80 (SD 0.76) mi kg(-1) or 4.7 (4.6)%, and a positive correlation was observed (r=0.91). We conclude that the CO method can be used to measure blood volume during perioperative periods in infants because it avoids use of a radioactive tracer, is simple and repeated measurements are possible.
PMID	10211023