コレマツ セイゴ   KOREMATSU Seigo
  是松 聖悟
   所属   埼玉医科大学  医学部 総合医療センター 小児科(小児科、総合周産期母子医療センター新生児科、小児救命救急センター)
   職種   教授
論文種別 学術雑誌(原著)
言語種別 英語
査読の有無 査読あり
表題 “Spike” in acute asthma exacerbations during enterovirus D68 epidemic in Japan: A nation-wide survey
掲載誌名 正式名:Allergology International
ISSNコード:14401592
出版社 Japanese Society of Allergology
巻・号・頁 67(1),55-60頁
著者・共著者 Seigo Korematsu,on behalf of the Japanese Society of Pediatric Allergy and Clinical Immunology,Kengo Nagashima,Yasunori Sato,Mizuho Nagao,Shunji Hasegawa,Haruna Nakamura,Shiro Sugiura,Katsushi Miura,Kenji Okada,Takao Fujisawa,the Japanese Society of Pediatric Allergy and Clinical Immunology
発行年月 2018/01
概要 Background In September 2015, Japan experienced an unusual increase in acute asthma hospitalizations of children that coincided with an enterovirus D68 (EV-D68) epidemic. The objective of this study is to investigate whether EV-D68 had a causal relationship with the spike in asthma hospitalizations. Methods A nation-wide retrospective survey of asthma hospitalizations of children was performed for the period from January 2010 through October 2015. The Japanese Society of Pediatric Allergy and Clinical Immunology asked its affiliated hospitals to report monthly numbers of hospitalizations, ICU admissions and mechanical ventilations due to acute asthma exacerbation. The data were retrieved from medical databases using predefined search criteria: diagnosis of asthma or asthmatic bronchitis, admission, and age&lt20 years. Monthly numbers of EV-D68 detection were also obtained from the Infectious Disease Surveillance Center of Japan. A Granger causality test was used to analyze the association of EV-D68 detections for asthma exacerbation. Results A total of 157 hospitals reported 87,189 asthma hospitalizations, including 477 ICU admissions and 1193 mechanical ventilations, during the
DOI 10.1016/j.alit.2017.04.003
PMID 28455155