コレマツ　セイゴ   KOREMATSU Seigo   是松　聖悟    所属   埼玉医科大学  医学部 総合医療センター　小児科（小児科､総合周産期母子医療センター新生児科、小児救命救急センター）    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Sex- and age-related differences in morbidity rates of 2009 pandemic influenza A H1N1 virus of swine origin in Japan.
掲載誌名	正式名：PloS one
巻・号・頁	6(4),e19409頁
著者・共著者	Nobuoki Eshima,Osamu Tokumaru,Shohei Hara,Kira Bacal,Seigo Korematsu,Minoru Tabata,Shigeru Karukaya,Yoshinori Yasui,Nobuhiko Okabe,Toyojiro Matsuishi
発行年月	2011/04
概要	BACKGROUND: The objective of the present study was to determine whether the morbidity rates of the 2009 pandemic influenza A H1N1 virus (pdmH1N1) varied by age and/or sex. METHODS AND FINDINGS: Retrospective analysis of 2,024,367 cases of pdmH1N1 was performed using the national surveillance data from influenza sentinel points in Japan. The male-to-female morbidity ratios (M/F ratios) in nineteen age groups were estimated as the primary outcome. The M/F ratios for pdmH1N1 influenza were:>1 in age groups<20 years and ≥80 years (p<0.001);<1 in age groups 20-79 years (p<0.001). This data suggests that males<20 years of age may be more likely to suffer from pdmH1N1 influenza than females in the same age categories. When the infection pattern for pdmH1N1 was compared with that of seasonal influenza outbreaks between 2000 and 2008, the M/F ratio for pdmH1N1 influenza was higher in ages 3-29 years and lower in ages 40-79 years. Because the present study was based on the national surveillance, it was impossible to estimate the morbidity rate for the Japanese population. It isalso likely that the data did not capture asymptomatic or mild infections. CONCLUSIONS: Although exposure to
DOI	10.1371/journal.pone.0019409
ORCIDのPut Code	15845350
PMID	21559366