タカイ　ヤスシ   TAKAI Yasushi   高井　泰    所属   埼玉医科大学  医学部 総合医療センター　産婦人科（産婦人科、総合周産期母子医療センター産科）    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Risk factors for neonatal bronchopulmonary dysplasia in extremely preterm premature rupture of membranes: a retrospective study
掲載誌名	正式名：BMC Pregnancy and Childbirth 略　 称：BMC Pregnancy Childbirth ISSNコード：14712393
掲載区分	国外
出版社	Springer Nature
巻・号・頁	20(662),online頁
総ページ数	9
著者・共著者	◎Eishin Nakamura, Shigetaka Matsunaga, Yoshihisa Ono, Yasushi Takai, Hiroyuki Seki
発行年月	2020/11/03
概要	Determination of the optimal timing for termination of pregnancy in cases of preterm premature rupture of membranes (pPROM) during the extremely preterm period is still difficult. Bronchopulmonary dysplasia (BPD) is a major disease widely taken into account when determining the prognosis of respiratory disorders in a neonate. Many aspects of this disease remain unclear. With the aim of further improving the prognosis of neonates born to mothers with pPROM, this study examined cases who were diagnosed with pPROM before 28 weeks of gestation. The study analysed risk factors for neonatal BPD. This study included 73 subjects with singleton pregnancy, diagnosed with pPROM during the gestational period from 22 weeks and 0 days to 27 weeks and 6 days. Our findings suggest that duration of oligohydramnios for more than 4 days before delivery and preterm delivery less than 24.1 weeks are risk factors for BPD in cases who are diagnosed with pPROM before 28 weeks of gestation.
DOI	10.1186/s12884-020-03366-0.
PMID	33143671