マエシマ　アキト   MAESHIMA Akito   前嶋　明人    所属   埼玉医科大学  医学部 総合医療センター　腎・高血圧内科    職種   教授
論文種別	学術雑誌(症例報告)
言語種別	英語
査読の有無	査読あり
表題	The Analysis of Renal Infiltrating Cells in Acute Tubulointerstitial Nephritis Induced by Anti-PD-1 Antibodies: A Case Report and Review of the Literature.
掲載誌名	正式名：Internal medicine (Tokyo, Japan) 略　 称：Intern Med
掲載区分	国内
巻・号・頁	57(21),3135-3139頁
著者・共著者	Tabei Akifumi, Watanabe Mitsuharu, Ikeuchi Hidekazu, Nakasatomi Masao, Sakairi Toru, Kaneko Yoriaki, Maeshima Akito, Kaira Kyoichi, Hirato Junko, Nojima Yoshihisa, Hiromura Keiju
発行年月	2018/11/01
概要	Nivolumab is an anti-programmed cell death-1 (PD-1) antibody that is utilized as an immune checkpoint inhibitor (ICI) for cancer therapy. We herein present the case of a 57-year-old man who developed acute kidney injury during treatment with nivolumab for lung cancer. A renal biopsy revealed acute tubulointerstitial nephritis. Immunohistochemical staining demonstrated marked infiltration of macrophages and T cells together with mild B cell infiltration. Of note, strong CD163+
DOI	10.2169/internalmedicine.0444-17
PMID	29877267