イノウエ イクオ
INOUE Ikuo
井上 郁夫 所属 埼玉医科大学 医学部 教職員・学生健康推進センター 職種 教授 |
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論文種別 | 学術雑誌(原著) |
言語種別 | 英語 |
査読の有無 | 査読あり |
表題 | Redox-dependent PPARγ/Tnpo1 complex formation enhances PPARγ nuclear localization and signaling. |
掲載誌名 | 正式名:Free radical biology&medicine 略 称:Free Radic Biol Med |
掲載区分 | 国外 |
巻・号・頁 | 156,45-56頁 |
著者・共著者 | Teratani Toshiaki, Tomita Kengo, Toma-Fukai Sachiko, Nakamura Yutaro, Itoh Toshimasa, Shimizu Hikaru, Shiraishi Yasunaga, Sugihara Nao, Higashiyama Masaaki, Shimizu Takahiko, Inoue Ikuo, Takenaka Yasuhiro, Hokari Ryota, Adachi Takeshi, Shimizu Toshiyuki, Miura Soichiro, Kanai Takanori |
発行年月 | 2020/06 |
概要 | The nuclear receptor peroxisome proliferator-activated receptor (PPAR)γ has been implicated in the pathogenesis of various human diseases including fatty liver. Although nuclear translocation of PPARγ plays an important role in PPARγ signaling, details of the translocation mechanisms have not been elucidated. Here we demonstrate that PPARγ2 translocates to the nucleus and activates signal transduction through H2 |
DOI | 10.1016/j.freeradbiomed.2020.06.005 |
PMID | 32553752 |