ヤマギシ　トシユキ   YAMAGISHI Toshiyuki   山岸　敏之    所属   埼玉医科大学  保健医療学部 臨床検査学科    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Follistatin-like 5 is expressed in restricted areas of the adult mouse brain: Implications for its function in the olfactory system
掲載誌名	正式名：CONGENITAL ANOMALIES ISSNコード：09143505
出版社	WILEY-BLACKWELL
巻・号・頁	54(1),63-66頁
著者・共著者	Tomoyuki Masuda,Chie Sakuma,Atsuko Nagaoka,Toshiyuki Yamagishi,Shuichi Ueda,Takahiro Nagase,Hiroyuki Yaginuma
発行年月	2014/02
概要	Follistatin-like 5 (Fstl5), a member of the follistatin family of genes, encodes a secretory glycoprotein. Previous studies revealed that other members of this family including Fstl1 and Fstl3 play an essential role in development, homeostasis, and congenital disorders. However, the in vivo function of Fstl5 is poorly understood. To gain insight into the function of Fstl5 in the mouse central nervous system, we examined the Fstl5 expression pattern in the adult mouse brain. The results of in situ hybridization analysis showed a highly restricted pattern of Fstl5, namely, with localization in the olfactory system, hippocampal CA3 area and granular cell layer of the cerebellum. Restricted expression in the olfactory system suggests a possible role for Fstl5 in maintaining odor perception.
DOI	10.1111/cga.12022
PMID	24588779