イタザワ トシコ   ITAZAWA TOSHIKO
  板澤 寿子
   所属   埼玉医科大学  医学部 小児科(小児科、新生児科)
   職種   准教授
論文種別 学術雑誌(原著)
言語種別 英語
査読の有無 査読あり
表題 Desert Dust Exposure Is Associated with Increased Risk of Asthma Hospitalization in Children
掲載誌名 正式名:AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
ISSNコード:1073449X
出版社 AMER THORACIC SOC
巻・号・頁 182(12),1475-1481頁
著者・共著者 Kumiko T. Kanatani,Isao Ito,Wael K. Al-Delaimy,Yuichi Adachi,William C. Mathews,Joe W. Ramsdell
発行年月 2010/12
概要 Rationale: Desert dust particles, including quartz, which causes inflammatory responses in the airway in animal studies, are transported to widespread regions around the globe. Epidemiologically, areas impacted by desert dust storms, such as communities in the Middle East and the Caribbean, seem to have higher incidences of asthma than might be expected.Objectives: We investigated the magnitude of association between airborne mineral dust concentration and hospitalization of children for asthma exacerbation by using Light Detection And Ranging (LIDAR) with a polarization analyzer for an exposure measurement, which can distinguish mineral dust particles from other particles. Methods: A case-crossover design was used. The exposure measurement was LIDAR's nonspherical extinction coefficient. The outcome measurement was hospitalization of children aged 1 to 15 years for asthma exacerbation in eight principal hospitals in Toyama, a local area in japan bordering the Japan Sea, during February to April, 2005 to 2009.Measurements and Main Results: During the study period, there were 620 admissions for asthma exacerbation, and 6 days with a heavy dust event (daily mineral dust concentrati
DOI 10.1164/rccm.201002-0296OC
PMID 20656941