オオヤマ　ゲンコウ   OYAMA Genko   大山　彦光    所属   埼玉医科大学  医学部 脳神経内科    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Unilateral GPi-DBS as a treatment for levodopa-induced respiratory dyskinesia in Parkinson disease.
掲載誌名	正式名：The neurologist
掲載区分	国外
巻・号・頁	17(5),282-5頁
著者・共著者	Genko Oyama,Kelly D Foote,Sanjay S Iyer,Pamela Zeilman,Nelson Hwynn,Charles E Jacobson,Irene A Malaty,Hubert H Fernandez,Ramon L Rodriguez,Michael S Okun
発行年月	2011/09
概要	BACKGROUND: Respiratory dyskinesia is a rare but disabling complication of levodopa therapy for Parkinson disease; however, its treatment has been limited to medication optimization. CASE REPORT: A 72-year-old woman with a 6-year history of Parkinson disease presented with severe and debilitating levodopa-induced respiratory dyskinesia, which manifested with a short and shallow breathing pattern and panting. These symptoms were observed coincident with limb and truncal dyskinesias. Both respiratory and limb/trunk dyskinesias were addressed by the implantation of a unilateral globus pallidus interna deep brain stimulator (GPi-DBS). CONCLUSIONS: Although the mechanism of involvement of the respiratory system in dyskinesia is unknown, GPi-DBS seems to be a potentially viable treatment option for these patients.
DOI	10.1097/NRL.0b013e318217367b
PMID	21881473