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コレマツ セイゴ
KOREMATSU Seigo
是松 聖悟 所属 埼玉医科大学 医学部 総合医療センター 小児科（小児科､総合周産期母子医療センター新生児科、小児救命救急センター） 職種 教授 |
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| 論文種別 | 学術雑誌(原著) |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Cell distribution differences of matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 in patients with Kawasaki disease. |
| 掲載誌名 | 正式名：The Pediatric infectious disease journal ISSNコード：08913668 |
| 出版社 | LIPPINCOTT WILLIAMS&WILKINS |
| 巻・号・頁 | 31(9),973-4頁 |
| 著者・共著者 | Seigo Korematsu,Yoko Ohta,Naotaka Tamai,Masahiro Takeguchi,Chika Goto,Hiroaki Miyahara,Tatsuya Kawano,Tatsuro Izumi |
| 発行年月 | 2012/09 |
| 概要 | The interaction of matrix metalloproteinase (MMP)-9 and tissue inhibitor of matrix metalloproteinase-1 has been implicated in the formation of coronary aneurysms in Kawasaki disease. MMP-9 and tissue inhibitor of matrix metalloproteinase-1 were distributed predominantly in the granulocytes and platelets, respectively, in patients with Kawasaki disease. The plasma values of MMP-9 correlated positively with the circulating neutrophil count. Inhibiting the activity of granulocytes and maintaining the platelet activity might prevent coronary aneurysms. |
| DOI | 10.1097/INF.0b013e31825ba6b3 |
| PMID | 22895216 |