マエシマ　アキト   MAESHIMA Akito   前嶋　明人    所属   埼玉医科大学  医学部 総合医療センター　腎・高血圧内科    職種   教授
論文種別	学術雑誌(総説)
言語種別	英語
査読の有無	査読なし
表題	Role of the activin-follistatin system in the morphogenesis and regeneration of the renal tubules.
掲載誌名	正式名：Molecular and cellular endocrinology 略　 称：Mol Cell Endocrinol
掲載区分	国外
巻・号・頁	180(1-2),179-182頁
著者・共著者	Kojima I, Maeshima A, Zhang Y Q
発行年月	2001/06
概要	Activin A inhibits branching tubulogenesis of the kidney during development. Activin A also inhibits branching tubulogenesis in MDCK cells, an in vitro tubulogenesis model. On the other hand, follistatin, an antagonist of activin A, reverses the effect of activin A and induces branching tubulogenesis. Follistatin also promotes tubular regeneration after ischemia/reperfusion injury. The activin/follistatin system is one of the important regulatory systems modulating developmental and regeneration processes of the kidney.
DOI	10.1016/s0303-7207(01)00511-1
PMID	11451589