マツサカ ヨウジ
MATSUSAKA Yohji
松坂 陽至 所属 埼玉医科大学 医学部 国際医療センター 放射線科(放射線腫瘍科、画像診断、核医学科) 職種 准教授 |
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論文種別 | 学術雑誌(原著) |
言語種別 | 英語 |
査読の有無 | 査読あり |
表題 | Impact of the cerebrospinal fluid-mask algorithm on the diagnostic performance of 123I-Ioflupane SPECT: an investigation of parkinsonian syndromes. |
掲載誌名 | 正式名:EJNMMI research |
巻・号・頁 | 9(1),85-85頁 |
著者・共著者 | Yu Iwabuchi,Tadaki Nakahara,Masashi Kameyama,Yohji Matsusaka,Yasuhiro Minami,Daisuke Ito,Hajime Tabuchi,Yoshitake Yamada,Masahiro Jinzaki |
発行年月 | 2019/09 |
概要 | BACKGROUND: A cerebrospinal fluid (CSF)-mask algorithm has been developed to reduce the adverse influence of CSF-low-counts on the diagnostic utility of the specific binding ratio (SBR) index calculated with Southampton method. We assessed the effect of the CSF-mask algorithm on the diagnostic performance of the SBR index for parkinsonian syndromes (PS), including Parkinson's disease, and the influence of cerebral ventricle dilatation on the CSF-mask algorithm. METHODS: We enrolled 163 and 158 patients with and without PS, respectively. Both the conventional SBR (non-CSF-mask) and SBR corrected with the CSF-mask algorithm (CSF-mask) were calculated from 123I-Ioflupane single-photon emission computed tomography (SPECT) images of these patients. We compared the diagnostic performance of the corresponding indices and evaluated whether the effect of the CSF-mask algorithm varied according to the extent of ventricle dilatation, as assessed with the Evans index (EI). A receiver-operating characteristics (ROC) analysis was used for statistical analyses. RESULTS: ROC analyses demonstrated that the CSF-mask algorithm performed better than the non-CSF-mask (no correction, area under the curv |
DOI | 10.1186/s13550-019-0558-x |
PMID | 31482376 |