マツサカ　ヨウジ   MATSUSAKA Yohji   松坂　陽至    所属   埼玉医科大学  医学部 国際医療センター　放射線科（放射線腫瘍科、画像診断、核医学科）    職種   准教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Evaluation of edge-preserving and noise-reducing effects using the nonlinear diffusion method in bone single-photon emission computed tomography.
掲載誌名	正式名：Nuclear medicine communications ISSNコード：01433636
出版社	Nuclear Medicine Communications
巻・号・頁	40(7),693-702頁
著者・共著者	Toshimune Ito,Masahisa Onoguchi,Yuji Ogata,Yohji Matsusaka,Takayuki Shibutani
発行年月	2019/07
概要	OBJECTIVES: This study aims to evaluate nonlinear diffusion (NLD) processing to smoothen images while suppressing resolution degradation in single-photon emission computed tomography (SPECT) images. Phantom data were used for NLD method optimization. The resultant optimal settings were used for NLD processing of clinical images. MATERIALS AND METHODS: Tc was used to simulate tumors and normal soft tissues. Using the data collected, images were reconstructed. Images were processed using various k values and iteration. The background region's coefficient of variation (CV) was determined, and the effects of parameters on image properties were examined. NLD-processed images with optimal parameters were compared with Butterworth (BW)-filtered and nine-point smoothing (SM)-processed images to evaluate smoothing filter properties in real and frequency space. Receiver operating characteristic curve analysis was carried out on NLD-processed and BW048-processed bone SPECT images. RESULTS: From CVs in background, with NLD, increased k value and iteration led to a low CV, indicating enhanced smoothing effect. At k=0.9, a strong noise-reducing effect with less iteration was achieved. Contrasts
DOI	10.1097/MNM.0000000000001028
PMID	31083012
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