ババ　ヤスタカ   BABA Yasutaka   馬場　康貴    所属   埼玉医科大学  医学部 国際医療センター　放射線科（放射線腫瘍科、画像診断、核医学科）    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Experimental renal and hepatic artery embolization with a new embolic agent, atelocollagen, in a porcine model
掲載誌名	正式名：DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY ISSNコード：13053825
出版社	TURKISH SOC RADIOLOGY
巻・号・頁	19(2),141-144頁
著者・共著者	Baba Yasutaka,Hayashi Sadao,Ikeda Shunichiro,Higashi Michiyo,Nakajo Masayuki
発行年月	2013/03
概要	PURPOSEWe aimed to investigate the potentiality of atelocollagen, a new embolic agent which is collagen type I in a porcine experimental model.MATERIALS AND METHODSThree pigs underwent transcatheter embolization of lower interlobular arteries of the renal artery (n=6) and one branch of the hepatic artery (n=3) with collagen type I. Angiography was performed prearterial, during, and postarterial embolization. After the procedure, samples from the embolized organs were evaluated by histological analysis.RESULTSSix lower interlobular renal arteries and three hepatic arteries were successfully embolized by administration of 0.8 +/- 0.3 mL and 2.9 +/- 1.2 mL, respectively, of the collagen type I. Histological findings of the embolized kidney specimens showed that the collagenous materials filled the arterial lumen, whose size ranged from 2.02 to 839.82 pm and reached the level of afferent arteries of glomerular tufts. Although the area of occluded arteries of the liver was smaller than the kidney, histological findings of the liver specimens showed that the collagenous materials filled small arterial lumens from 2.81 to 187.86 mu m in diameter.CONCLUSIONAtelocollagen, a collagen
DOI	10.4261/1305-3825.DIR.6086-12.1