ババ　ヤスタカ   BABA Yasutaka   馬場　康貴    所属   埼玉医科大学  医学部 国際医療センター　放射線科（放射線腫瘍科、画像診断、核医学科）    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Are catecholamine-derived indexes in adrenal venous sampling useful for judging selectivity and laterality in patients with primary aldosteronism?
掲載誌名	正式名：ENDOCRINE ISSNコード：1355008X
出版社	HUMANA PRESS INC
巻・号・頁	43(3),611-617頁
著者・共著者	Yasutaka Baba,Sadao Hayashi,Masayuki Nakajo
発行年月	2013/06
概要	In order to investigate retrospectively whether catecholamine concentrations obtained by adrenal venous sampling (AVS) are useful for lateralization of the aldosteronoma-bearing adrenal gland. The study population comprised 35 patients (10 men, 25 women; mean age, 49.8 years) with aldosteronoma and 18 patients (9 men, 9 women; mean age, 51.8 years) with non-functioning adenoma who underwent AVS between 1994 and 2010. In all cases, AVS was performed without administering adrenocorticotrophic hormone. Successful or unsuccessful adrenal vein blood sampling (selectivity) was judged by the ratio of plasma cortisol (C) level in each adrenal vein to that in the infra-renal inferior vena cava [C(side)/C(IVC)]as a gold standard, with successful selectivity defined using four different cut-off values [C(side)/C(IVC) a parts per thousand yen 3.0, 2.0, 1.36 or 1.1]. Receiver operating characteristics (ROC) analyses were conducted to determine: (1) degree of selectivity; and (2) the best catecholamine (epinephrine, norepinephrine, and dopamine)-derived index for lateralization of the aldosteronoma-bearing adrenal gland. Among the catecholamine-derived indexes, the epinephrine concentration rat
DOI	10.1007/s12020-012-9793-x